Explore Ectoine – Natural Protection for Your Cells

Ectoine is a naturally occurring molecule that protects cells from environmental stressors, such as UV radiation, pollution, and extreme temperatures. Santa Biotech’s fermentation-based production ensures a sustainable, pure, and highly effective ingredient, making it an ideal addition for industries looking to enhance skin health, hydration, and protection.

Explore Ectoine: Your Complete Guide

This section provides a comprehensive overview of ectoine, from its protective properties to its global regulatory status. Whether you’re interested in its skin-protecting capabilities, formulation guidance, or its approval across international markets, our detailed guide will help you make informed decisions. Discover why ectoine is the perfect choice for your cosmetic and skincare products.

How to Choose High-Quality Ectoine for Your Products

When it comes to sourcing Ectoine, ensuring you choose a high-quality product is essential for optimal performance in your formulations. Whether you are manufacturing cosmetics, supplements, or skincare products, knowing what to look for in raw Ectoine can make a significant difference in your product’s effectiveness.

Look for These Key Quality Indicators:

  • Purity: Look for Ectoine with a purity level of at least 99% to ensure that the raw material is free from contaminants and unwanted by-products.
  • Stable Structure: A high-quality Ectoine should have a stable crystalline structure that maintains its integrity in different formulations.
  • Solubility: Ectoine should dissolve effectively in water-based formulations without clumping or leaving residues.
  • Origin and Certification: Ensure your Ectoine comes from a reputable supplier that uses eco-friendly, fermentation-based production methods and provides necessary certifications

Production Methods Matter:

Ectoine can be produced using several methods, but the most reliable process is biological fermentation. This eco-friendly method ensures high purity and stability, making it suitable for a wide range of applications, from cosmetics to health supplements.

Why Choose Santa Biotech’s Ectoine?

Santa Biotech’s Ectoine is produced through advanced fermentation technology, resulting in a product with exceptional stability and purity (≥99%). Our green production process is sustainable and cost-effective, providing you with a premium ingredient for your formulations.
By choosing Santa Biotech’s Ectoine, you benefit from:

  • High purity and stability: Ensuring consistency in your formulations.
  • Cost-effective production: Lower costs without sacrificing quality.
  • Non-toxic and eco-friendly: Free from harmful impurities and environmentally sustainable.

Why Choose Ectoine? Nature’s Cellular Protector

Natural Origin
Ectoine is a natural protective molecule found in microorganisms that thrive in extreme environments (extremophiles), providing a powerful protective barrier for skin cells.
Ectoine protects cellular structures by stabilizing cell membranes and preventing the loss of moisture, keeping the skin hydrated even under harsh conditions.
Ectoine helps maintain moisture balance in the skin by acting as a moisture-binding agent, leading to improved skin elasticity and reduced roughness.
Known for its ability to shield cells from UV radiation, pollution, and other environmental stressors, ectoine is a powerful active ingredient for anti-aging and sun-care products.
Ectoine is non-irritating and suitable for all skin types, making it a preferred choice for sensitive and dry skin formulations.

Ectoine Specifications: Explore the Key Details

Santa Biotech’s ectoine is produced to meet the highest international standards, including compliance with both European (EU) and U.S. (USP) quality regulations. Our ectoine appears as a white crystalline powder that is highly soluble in water, making it an excellent choice for a wide range of cosmetic and skincare formulations.
Ectoine Specifications
Santa Biotech’s Ectoine is a highly pure (99%+) natural ingredient produced using advanced synthetic biology fermentation technology. It comes as a white crystalline powder that is water-soluble and stable under various conditions, making it perfect for use in skincare, cosmetics, and health products. Ectoine provides long-lasting hydration and skin protection, and it meets international quality standards such as GMP and ISO. Packaged securely for optimal freshness and stability, it’s the ideal choice for enhancing your product formulations with proven efficacy.

Parameter

ItemSpecificationMethod
AppearanceWhite CrystalVisual observation
SmelCharacteristic odorNose smells
Purity>99.9%HPLC
pH (50 mg/mL, 20°C)6.0-7.5pH meter
Melting point (Decompose)270-271°CMelting point detector
Optical rotation[α]D≥(+)122°(c=1,H2O)Polarimeter
Crystallite size100% pass rate for 50 meshSieve
Density0.55-0.75 g/mLBulk density meter
Loss on drying< 0.5%TGA
Total residual solvents (Ethanol)<200ppmGC
Arsenic≤1.0 ppmICP
Lead≤1.0 ppmICP
Mercury<0.2 ppmICP
Cadmium<0.3 ppmICP
Total heavy metals≤ 10 ppmICP
E.ColiNegative/25gUSP<62>
Staphylococcus aureus RosenbachNegative/25gUSP<62>
P. aeruginosaNegative/25gUSP<62>
SalmonellaNegative/25gUSP<62>
Total coliform<100 CFU/gAOAC
Total yeast and mold count<100 CFU/gUSP<61>
Total viable aerobic count<1000 CFU/gUSP<61>

Package

100G/Bag 500G/Bag 1KG/Bag

Storage Condition

Store in cool and dry place at temperature 0 to 20℃, keep away from strong light

Shelf life

2 Years

Global Products with Ectoine

Ectoine is trusted by many leading brands worldwide for its skin-protecting properties. Some notable products containing ectoine include:
This popular skincare brand incorporates Ectoine into its formula to help soothe sensitive skin, reduce inflammation, and restore the skin’s natural barrier, making it ideal for people with allergies or skin irritations.
Ectoine is a key ingredient in this repair ointment, helping to protect and repair damaged or dry skin while providing long-lasting moisture.
A well-known brand in Europe, Balea uses Ectoine in its Aqua Serum to boost skin hydration and protect against environmental stressors, offering a refreshing and moisturizing experience.
These luxury sun protection drops contain Ectoine, which works to protect the skin from UV damage while deeply hydrating and promoting overall skin health.
Known for its skin-soothing properties, Bepanthol includes Ectoine in its intensive body lotion to support long-lasting hydration and repair for dry, sensitive skin.

How Ectoine Makes End Products Better

Ectoine is a versatile and powerful ingredient that can significantly improve the performance of a wide range of products. Its unique protective and moisturizing properties make it a valuable addition to formulations in several industries:

Skincare Products

Ectoine helps retain moisture within the skin, offering long-lasting hydration. This makes it an essential ingredient in skincare products like creams, serums, and lotions, providing immediate and sustained moisture for dry and sensitive skin.

Sun Care Products

Ectoine acts as a cellular protectant, shielding skin cells from environmental stressors such as UV radiation, pollution, and temperature changes. This helps reduce inflammation and prevent damage, making it ideal for anti-aging and sun care products.

Personal Care Products

Ectoine is highly compatible with various formulations, from creams and serums to sun care and after-sun products. Its multifunctional benefits enhance overall product efficacy, making it a standout ingredient in both skincare and personal care products.

Skin Treatments Products

With its ability to reduce redness, irritation, and inflammation, Ectoine is often used in formulations designed for people with sensitive, reactive, or allergy-prone skin, improving comfort and appearance.

How Ectoine Works Synergistically With Other Ingredients

Ectoine enhances the efficacy of other ingredients by acting as a powerful cell protectant and hydrator, creating a more balanced environment for the skin. When combined with:

  • Hyaluronic Acid: Ectoine boosts hydration levels, creating a dual-action moisturizing effect that helps the skin retain moisture for longer periods.
  • Niacinamide: Ectoine works well with niacinamide to enhance the skin barrier, providing protection from environmental stressors while reducing inflammation and irritation.
  • Antioxidants (e.g., Vitamin C, Vitamin E): Ectoine enhances the antioxidant defense system, providing greater protection against free radicals and oxidative stress, which contributes to anti-aging effects.
  • Sunscreens: When used in sun protection products, Ectoine enhances the effectiveness of UV filters by reducing the damaging effects of UV rays on skin cells and aiding in skin repair.

What Are The Regulations Surrounding Ectoine In Different Regions?

Ectoine is widely approved for use in cosmetics in major markets such as the European Union (EC No 1223/2009), the U.S. (FDA guidelines), Japan, China (NMPA), Australia, and Canada. It is considered a safe and effective ingredient in skincare, especially for sensitive skin, anti-aging, and sun protection formulations.

Understanding Ectoine Production Technology

At Santa Biotech, we use advanced synthetic biology fermentation technology to produce Ectoine, ensuring a high-quality, eco-friendly, and sustainable ingredient. This cutting-edge production method replicates natural processes, resulting in highly pure Ectoine with consistent efficacy.
What makes synthetic biology fermentation superior for Ectoine production compared to traditional methods?
Synthetic biology fermentation is superior because it mimics the natural environment in which halophilic bacteria produce Ectoine. This method results in higher purity, better sustainability, and fewer impurities compared to traditional chemical synthesis. It also allows for a more consistent production process, ensuring uniform quality across batches, which is crucial for high-performance formulations.
During fermentation, the bacteria synthesize Ectoine under controlled conditions, allowing for precise monitoring of the process. This results in fewer byproducts and contaminants, achieving a purity level of over 99%. The entire process is optimized to minimize impurities, which enhances the quality and performance of Ectoine in end products.
Fermentation technology is more eco-friendly than chemical synthesis because it uses renewable feedstocks (like sugars) and produces less waste. The process is also energy-efficient and generates fewer harmful byproducts, reducing the environmental impact. This aligns with the goals of sustainable and clean beauty production, making it a preferred method for eco-conscious brands.
The fermentation process produces Ectoine that is highly stable and bioactive. The controlled environment ensures that the product retains its structural integrity, resulting in long-term stability in formulations. This means that Ectoine continues to provide moisturizing, protective, and anti-aging benefits even after extended periods of storage and use.
Quality control measures include real-time monitoring of temperature, pH, and nutrient levels during fermentation to ensure optimal bacterial growth. After production, each batch undergoes rigorous testing for purity, consistency, and absence of contaminants. Adherence to GMP (Good Manufacturing Practices) and ISO standards ensures that every batch meets strict quality criteria.
Yes, advancements in genetic engineering and process optimization are helping to further improve Ectoine production. For example, CRISPR technology allows for the creation of more efficient bacterial strains that can produce higher yields of Ectoine. Additionally, innovations in bioprocess automation and AI-driven monitoring are making the fermentation process more efficient and scalable.
Fermentation aligns perfectly with clean beauty principles because it uses natural processes and minimizes the use of harmful chemicals or synthetic inputs. The process is sustainable, utilizing renewable resources, and results in minimal waste and emissions. This makes Ectoine produced via fermentation an ideal ingredient for brands promoting eco-friendly and safe products.
Scaling fermentation can be challenging due to the need for precise control over the production environment. It requires significant investment in bioreactors and monitoring systems to maintain optimal conditions for bacterial growth at a larger scale. Additionally, maintaining consistent quality across larger batches can be complex, but advancements in automation and real-time monitoring are helping to address these challenges.

Ectoine Regulations: Where It’s Approved

Ectoine is widely recognized as a safe and effective ingredient in skincare and health products, with approvals in major global markets. Here’s a breakdown of where Ectoine is approved and the relevant regulatory numbers:

Key Compliance Markets:

1. European Union
Regulation: Ectoine is approved under the Cosmetics Regulation (EC) No 1223/2009, which ensures safety for use in cosmetic products. It is widely used in skincare, anti-aging, and sun care formulations across the EU.
Approval Number: EC No 1223/2009

2. United States
Regulation: Ectoine is approved by the Food and Drug Administration (FDA) for use in cosmetic products. It is considered safe and is used in a wide range of skincare and personal care formulations.
Approval Reference: FDA Cosmetic Ingredient Review (CIR) safety assessment reports

3. Japan
Regulation: Approved under Japan’s Standards for Cosmetics by the Ministry of Health, Labour, and Welfare (MHLW). Ectoine is commonly found in Japanese beauty products, particularly for sensitive and aging skin.
Approval Number: MHLW Notification No. 331

4. China
Regulation: Ectoine is listed as a safe cosmetic ingredient under China’s National Medical Products Administration (NMPA) guidelines. It is used in formulations targeting hydration and skin protection.
Approval Reference: Included in the Inventory of Existing Cosmetic Ingredients in China (IECIC)

5. Australia
Regulation: Approved by the Therapeutic Goods Administration (TGA) for use in personal care and skincare products. It is regulated under the Australian Cosmetics Standard 2007.
Approval Reference: TGA Cosmetics Standard 2007

6. Canada
Regulation: Approved for use in cosmetic products under Health Canada’s regulatory framework. Ectoine is commonly used in moisturizing and anti-aging products.
Approval Reference: Listed in the Hotlist of Cosmetic Ingredients as safe for use.

Easy Tips for Adding Ectoine to Your Products

Recommended Usage

Ectoine is typically used in concentrations ranging from 0.2% to 1.0% depending on the product type. For deep hydration and enhanced skin protection, consider using higher concentrations in serums and creams.

Compatibility and Synergistic Ingredients

Ideal Pairings: Ectoine works well with ingredients like hyaluronic acid (for boosted hydration), niacinamide (for improved skin barrier function), and antioxidants such as Vitamin C and Vitamin E (for enhanced protection against environmental stress).

Formulation Stability

  • pH Range: Ectoine is stable in a pH range of 5.0 to 7.0, making it suitable for most skincare and personal care formulations. It retains its efficacy in these conditions, ensuring long-term product stability.
  • Temperature Tolerance: Ectoine is resistant to high temperatures, allowing for flexibility during production processes that require heat.

Our Promise: High-Quality Ectoine Every Time

Certified Quality, Trusted by Global Brands

Santa Biotech ensures that every batch of ectoine is tested for purity, stability, and performance. Our production facilities are certified to meet international quality standards, offering peace of mind to B2B customers.

Our Quality Assurance Includes:

  • ISO22000 Certificated
  • Comprehensive Batch Testing for Purity and Potency
  • Certificates of Analysis (COA) Provided with Every Shipment
  • Transparent Supply Chain for Reliable Sourcing

Frequently Asked Questions About Ectoine

A Simple Guide to the Science Nervonic Acid

Ectoine is a natural molecule produced by halophilic bacteria to protect themselves from extreme environmental stress. In skincare and personal care products, Ectoine helps retain moisture, protect cells from damage caused by UV radiation and pollution, and strengthen the skin barrier, making it an ideal ingredient for hydration, anti-aging, and sensitive skin formulations.
Ectoine is highly versatile and can be used in a wide range of products, including:Moisturizers and creams,Serums and lotions,Sunscreens and after-sun care,Anti-aging formulations Personal care products like shampoos and conditioners
The recommended concentration of Ectoine ranges from 0.2% to 1.0%, depending on the product type and desired effects. Higher concentrations (around 1.0%) are typically used in serums and creams for intensive hydration and skin protection.
Yes, Ectoine is well-tolerated by sensitive skin. It has anti-inflammatory properties that help reduce redness, irritation, and discomfort, making it a great option for sensitive skin, eczema-prone skin, or post-treatment care.
Ectoine is produced through a sustainable fermentation process that uses natural feedstocks and generates minimal waste. This eco-friendly production method ensures that Ectoine aligns with the principles of clean beauty and sustainability.
Ectoine is approved for use in cosmetics and personal care products across major global markets: European Union: Compliant with Cosmetics Regulation (EC) No 1223/2009. United States: Approved under FDA Cosmetic Ingredient Review (CIR). Japan: Listed under MHLW Notification No. 331. China: Listed in the Inventory of Existing Cosmetic Ingredients in China (IECIC).
Ectoine stands out for its dual-action approach—retaining moisture within the skin while also protecting cells from environmental stress. This makes it a more comprehensive solution compared to traditional humectants like hyaluronic acid, which primarily focus on hydration.

Ask Free Sample

Get a 5g Free Sample of Our Nervonic Acid With a Testing Report

Get In Touch

Get In Touch